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Home / Blog / Can You Develop an Allergy to Alcohol Later in Life?

Can You Develop an Allergy to Alcohol Later in Life?

Posted by Penn Medicine Becker ENT & Allergy

It’s possible for adults to notice allergic reactions to alcoholic beverages, even if they’ve never had issues before. Though true alcohol allergies are rare, they still occur and can cause severe symptoms like rashes, trouble breathing, stomach cramps, collapse, or anaphylaxis.

Penn Medicine Becker ENT & Allergy’s nationally recognized allergy specialists bring deep expertise in identifying triggers and advising on care for late-onset reactions. Get in touch by visiting one of our more than 17 offices.

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Woman examining a wine bottle in a store aisle, checking the label carefully.
An alcohol allergy is an immune response where the body identifies alcohol as a harmful intruder.
⚠️ Important Medical Notice

The information provided below and throughout this website is presented for general educational purposes only and does NOT constitute professional medical advice. This information is NOT a substitute for professional medical advice and NO material on this site is intended to be a substitute for professional medical advice. Always seek the guidance of your doctor or other qualified health professional with any questions you may have regarding a health or a medical condition. Never disregard the advice of a medical professional or delay in seeking it because of something you have read on this website.

According to The American Academy of Allergy, Asthma & Immunology, True alcohol allergies are quite rare, under 1% of the global population.

Can you become allergic to alcohol later in life?

Yes, it’s possible to react to alcohol even if you never had a problem before.

Most of the time it’s not a “true allergy” but more of an intolerance or sensitivity. This can show up as things like flushing, headaches, feeling sick, or a racing heartbeat after drinking. If new symptoms show up, it’s smart to check with a doctor.

Why it can happen later

Enzymes: Your body uses enzymes to break down alcohol. If they don’t work well, alcohol builds up and makes you feel bad.
Genetics: Some people are born with a tendency to react, but it may not show up until later.
Health changes: Issues with your liver, stomach, or other health conditions can make alcohol harder to handle.
Medicines: Some meds mix badly with alcohol and trigger reactions.
Getting older: As we age, our body processes alcohol more slowly.

Allergy vs Intolerance

Allergy: Rare, but can cause hives, swelling, or trouble breathing.
Intolerance: Much more common — things like flushing, nausea, or headaches.

What to do:

Talk to a doctor if you notice new or strong reactions.
IntoleranPay attention to what you drank — sometimes it’s not the alcohol itself but things like sulfites or other ingredients.ce: Much more common — things like flushing, nausea, or headaches.

Can you be allergic to vodka?

Yes, you can be allergic to alcohol or to ingredients in vodka, though a true allergy to alcohol itself is rare.

More often, people have intolerance, which means their body struggles to break down alcohol, or they react to things in the vodka like grains, sulfites, or added flavorings. Symptoms can include hives, flushing, nausea, stomach pain, or even trouble breathing.

Symptoms

Skin reactions: hives, rash, flushing, itching.
Breathing issues: stuffy nose, sneezing, wheezing.
Stomach problems: nausea, cramps, diarrhea.
Heart symptoms: fast heartbeat, dizziness, fainting.
Severe cases: very rarely, anaphylaxis (serious allergic reaction).
Frosted vodka bottle and shot glass with ice cubes, illustrating alcohol allergy and intolerance discussion.
Alcohol allergies are rare, but reactions to vodka ingredients like grains or sulfites are more common.

Causes of reactions:

True alcohol allergy: the immune system reacts to alcohol.
Intolerance: missing enzymes to break down alcohol, causing flushing and discomfort.
Ingredient allergies: wheat, corn, sulfites, histamines, or flavorings in certain vodkas.

What to do:

Avoid the drink that causes issues, talk to a doctor or allergist, and in rare cases of severe reaction, carry an epinephrine injector.

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Can you be allergic to wine?

More often, people react to compounds in wine such as sulfites, histamines, tannins, or proteins from grapes and yeast. These can lead to flushing, headaches, rashes, stuffy nose, or stomach problems.

Common triggers

Sulfites: preservatives that may worsen asthma.
Histamines: can cause flushing, headaches, and congestion.
Yeasts and cork spores: possible allergic triggers.
Grape proteins: rare, but can cause true allergic reactions.

Symptoms

Skin: flushing, hives, itching, redness.
Nose/lungs: sneezing, congestion, wheezing.
Digestive: nausea, cramps, diarrhea.
Headaches or migraines.
Woman in blue sweater smelling a glass of red wine, highlighting wine allergy triggers like sulfites and histamines.
Sulfites, histamines, and grape proteins in wine can trigger allergic reactions or intolerance symptoms.

True allergy vs intolerance

Allergy: immune reaction, can be serious.
Intolerance: body struggles to process compounds like sulfites or histamines.

What to do:

If you react, see a doctor or allergist. They can test whether it’s a true allergy or intolerance.

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Can you get a rash from alcohol?

Yes, alcohol can cause rashes.

This may be from alcohol intolerance, an allergy to something in the drink, or because alcohol worsens an existing skin condition. Rashes can look like flushing, hives, red itchy patches, or dry, flaky skin.

Causes of alcohol-related rashes

Alcohol intolerance: a genetic issue with breaking down alcohol, causing redness and rashes.
Allergic reaction: to grapes, grains, hops, or additives.
Skin conditions: alcohol can flare eczema, psoriasis, or rosacea.
Flush reaction: alcohol causes blood vessels to widen, leading to redness and hives.
Person scratching arm while wearing striped shirt, illustrating skin rash caused by alcohol intolerance or allergic reaction.
Alcohol can trigger rashes due to intolerance, allergies, or by worsening existing skin conditions.

Symptoms to look for

True alcohol allergy: the immune system reacts to alcohol.
Itchy bumps or hives.
Dry or scaly patches.
Burning or irritation.

When to see a doctor

Always check with a doctor if you get new rashes from drinking. Seek urgent help if you also have swelling, trouble breathing, dizziness, or fainting.

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What Is an Alcohol Allergy?

An alcohol allergy occurs when the immune system mistakenly identifies alcohol as a harmful substance, triggering an allergic reaction. This reaction involves the production of allergy-specific antibodies. Common allergens in alcoholic beverages that can cause such reactions are barley, hops, yeast, rye, wheat, gluten, and sulfites.

These allergens can be present in various types of alcohol, so it is essential for individuals with an alcohol allergy to carefully read beverage labels and understand the ingredients. Apart from the usual triggers, you might also be affected by other ingredients—like leftovers from the fermentation process, artificial fruit flavors, or even seafood proteins—that can set off allergic reactions. Keep an eye out for these possible culprits to reduce the risk of unwanted symptoms.

How is Alcohol Allergy Different from Alcohol Intolerance?

An allergy to alcohol occurs if your immune system responds negatively to alcohol, bringing signs such as hives, swelling, or difficulty with breathing. Alcohol intolerance, however, is present if your body has issues breaking down alcohol as it should. This is most often because of one’s genetics. It can cause unpleasant reactions, such as flushing or feeling sick.

Sometimes, what looks like intolerance might be a reaction to specific ingredients, such as chemicals, grains, or preservatives in the drink. Common signs of alcohol intolerance include flushed skin, hives, worsened asthma, stuffy nose, low blood pressure, nausea, vomiting, and diarrhea.

Alcohol allergy can cause severe reactions like hives and anaphylaxis.
It differs from intolerance, involving an immune system reaction to alcohol.

Not sure if alcohol is making you feel off?

Contact the expert allergists at Penn Medicine Becker ENT & Allergy. We’re here to provide answers, care, and lasting relief.

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What Are the Symptoms of Alcohol Allergy and Intolerance?

The symptoms of an alcohol allergy can vary widely, ranging from mild intolerances to severe, dangerous allergic reactions. On the other hand, symptoms of alcohol intolerance, a more common condition, can be uncomfortable and sometimes severe.

Symptoms of Alcohol Allergy

Itchy rashes
Trouble breathing
Stomach upset
Life-threatening anaphylactic reaction
Shortness of breath
Loss of consciousness

Symptoms of Alcohol Intolerance

Facial redness (flushing)
Warmth or redness on the neck, chest, or face
Headache
Nausea
Vomiting
Fast heartbeat

What Risk Factors Can Lead to Alcohol Allergy Later in Life?

Certain factors can increase the risk of developing an allergy to alcohol later in life. These factors include age, genetic predisposition, pre-existing health conditions, and excessive alcohol consumption.

Individuals of Asian descent, those with asthma or hay fever, or those with allergies to grains or other foods are at higher risk for alcohol intolerance.

Age Group at Higher Risk

Although an alcohol allergy can start at any age, certain groups face a higher chance of developing one. If you’re a young adult who drinks heavily, watch for warning signs like facial redness, itchy skin bumps, or an upset stomach. Many people between 20 and 40 notice more alcohol-related issues because of heavier drinking patterns.

As you get older, you may suddenly find yourself more sensitive to alcohol if your body produces less of the enzyme that helps break it down. Researchers are still examining which ages are most vulnerable and why these allergies and intolerances happen.

Noticing unusual reactions to alcohol? Contact us for expert guidance today!

Alcohol allergy symptoms often appear in adults aged 20-40 due to higher alcohol consumption.
Young to middle-aged individuals are at higher risk for alcohol allergies from cumulative exposure.

Genetic Predisposition

Your genes can play a major role in whether you develop an alcohol allergy or intolerance. Many East Asians face a higher chance of alcohol intolerance because of reduced ALDH2 enzyme levels. According to a Cedars-Sinai piece by Nikolas Charles, around 30%-50% of this population experiences these reactions, often called “Asian flush” or “Asian glow.” This enzyme helps break down harmful substances in alcohol.

Key points about this process include:

  • Enzyme efficiency: Individuals with a fully active ALDH2 enzyme can metabolize alcohol efficiently, reducing the likelihood of adverse reactions.
  • Deficiency Effects: Those with an ALDH2 deficiency are more prone to experience symptoms like facial flushing, nausea, and rapid heartbeat after consuming alcohol.
Woman with facial flushing touching her cheek, illustrating a symptom of alcohol intolerance due to ALDH2 deficiency.
ALDH2 deficiency can cause facial flushing, nausea, and rapid heartbeat after alcohol consumption.

Experiencing alcohol sensitivity? Our experts can help—contact us for answers today!

Pre-existing Health Conditions

Certain medical conditions can exacerbate alcohol intolerance. These include:

  • Asthma: People with asthma may experience worsening of their symptoms after consuming alcohol.
  • Allergic Rhinitis: This condition can lead to an increased sensitivity to alcohol.
  • Hodgkin’s Lymphoma: Patients with this type of cancer may develop alcohol intolerance.
  • Enzyme Deficiency: Some people lack other enzymes necessary for alcohol metabolism, leading to similar symptoms.

Health conditions can worsen alcohol intolerance. Penn Medicine, Becker, and allergy specialists can help—reach out today!

Woman with asthma using an inhaler while sitting at home, managing breathing difficulty effectively.
Asthma symptoms can worsen after consuming alcohol.

Excessive Alcohol Consumption

Excessive alcohol consumption poses not only the risk of developing an alcohol allergy but also a myriad of other health complications. These complications can vary in severity, ranging from mild intolerances to more severe allergies and other adverse effects on the body. It is essential for individuals to be mindful of their alcohol intake and its potential impact on their health.

Practicing moderation and being aware of any adverse reactions to alcohol can help individuals make informed choices about their alcohol consumption and overall well-being.

Your health comes first. If alcohol is causing unexpected reactions, our experts are here to help!

Drinking too much alcohol increases histamine release, leading to severe allergic reactions.
Excessive alcohol consumption can worsen allergy symptoms like flushing, itching, and congestion.

Find Relief from Alcohol Allergy Symptoms with Trusted Care

Struggling with uncomfortable reactions to alcohol? You’re not alone—let’s work together to uncover the cause and find a solution.

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How Is an Alcohol Allergy Diagnosed and Treated?

Your doctor will begin with a complete medical background assessment. It helps to understand the signs you show along with any possible triggers. This assessment includes questions on alcohol drinking habits. It also concerns the kinds of drinks consumed and if relatives had allergies as well as intolerances.

The physical exam is another crucial step in the diagnostic process. Your doctor will look for signs of allergic reactions, such as skin rashes or hives, and check for other symptoms like swelling or respiratory issues. In some cases, your doctor may observe how your body reacts to a controlled amount of alcohol to identify any immediate symptoms.

To pinpoint the exact cause of your symptoms, your doctor might recommend several diagnostic tests, including:

  • Allergy tests: Skin prick tests or blood tests to check for specific allergic reactions.
  • Elimination diet: Temporarily removing alcohol from your diet to see if symptoms improve.
  • Challenge tests: Gradually reintroducing alcohol under medical supervision to monitor reactions.

These tests help determine whether your symptoms are due to an alcohol allergy, alcohol intolerance, or another underlying condition.

What Is It Like to Live with an Alcohol Allergy That Starts Later in Life?

Living with a newly developed alcohol allergy calls for extra vigilance and preparation. It’s important to pay close attention to what you consume and have a plan in place for potential reactions. Key steps include:

  • Informing family, friends, and dining establishments about your allergy to ensure your safety.
  • Regular check-ups with an allergist to manage symptoms and prevent severe reactions.

Although many people are aware of alcohol intolerance—which can cause nausea, headaches, and facial flushing—it’s also possible to develop a full-blown alcohol allergy later in life. True alcohol allergies, while rare, may trigger severe reactions like trouble breathing, hives, or even anaphylaxis.

If you’re looking for an allergy clinic in Robbinsville, NJ, we serve the areas of Hamilton, Florence, Georgetown, Bordentown, or Allentown. Penn Medicine Becker ENT & Allergy offers comprehensive allergy services and can help you manage your late-onset alcohol allergy efficiently. Contact us today and schedule a consultation.

Frequently Asked Questions About Alcohol Allergy

Can certain types of alcohol trigger more severe allergic reactions than others?

Yes, certain alcoholic beverages can trigger more severe reactions due to their histamine and sulfite content. According to Medical News Today, red wine has higher levels of these compounds, which can cause headaches, nasal congestion, or skin flushing in sensitive individuals.
People with asthma or hay fever may be more prone to reactions from histamines in red wine. Additionally, sulfites, commonly used as preservatives in wine, can lead to respiratory or skin issues. If you experience symptoms, consulting a healthcare professional is recommended.

Are there any non-alcoholic beverages that can cause similar allergic reactions?

Yes, non-alcoholic beverages like grape juice and certain soft drinks can also contain sulfites and histamines, which may trigger reactions in susceptible individuals.

Can an alcohol allergy be mistaken for a different medical condition?

Symptoms of an alcohol allergy can be similar to those of other conditions such as food allergies, alcohol intolerance, or even conditions like rosacea, which can cause facial flushing.

Is it possible to develop an alcohol allergy later in life even if you had no issues previously?

Yes, alcohol allergies can develop at any age, even if you have previously consumed alcohol without any problems. Changes in the immune system or repeated exposure to certain allergens can trigger this.

How can one differentiate between an alcohol allergy and alcohol intolerance?

Alcohol allergy typically involves an immune system response, leading to symptoms like hives, swelling, and difficulty breathing. In contrast, alcohol intolerance, often due to enzyme deficiencies, usually causes symptoms like facial flushing, nausea, and headache.

The content, including but not limited to, text, graphics, images and other material contained on this website is for informational purposes only. No content on this website is intended to be a substitute for professional medical advice, diagnosis, or treatment, nor represent the opinion of our physicians. Always seek the guidance of a qualified healthcare provider for any medical condition or concern.

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